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Structural confirmation of sulconazole sulfoxide as the primary degradation product of sulconazole nitrate
Sulconazole has been reported to degrade into sulconazole sulfoxide via sulfur oxidation; however, structural characterization data was lacking and the potential formation of an N-oxide or sulfone could not be excluded. To clarify the degradation pathways and incorporate the impurity profile of sulc...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Xi'an Jiaotong University
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934740/ https://www.ncbi.nlm.nih.gov/pubmed/29736295 http://dx.doi.org/10.1016/j.jpha.2017.12.007 |