MARCH6 and TRC8 facilitate the quality control of cytosolic and tail‐anchored proteins

Misfolded or damaged proteins are typically targeted for destruction by proteasome‐mediated degradation, but the mammalian ubiquitin machinery involved is incompletely understood. Here, using forward genetic screens in human cells, we find that the proteasome‐mediated degradation of the soluble misf...

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Detalles Bibliográficos
Autores principales: Stefanovic‐Barrett, Sandra, Dickson, Anna S, Burr, Stephen P, Williamson, James C, Lobb, Ian T, van den Boomen, Dick JH, Lehner, Paul J, Nathan, James A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934766/
https://www.ncbi.nlm.nih.gov/pubmed/29519897
http://dx.doi.org/10.15252/embr.201745603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934766/
https://www.ncbi.nlm.nih.gov/pubmed/29519897
http://dx.doi.org/10.15252/embr.201745603

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