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Towards development of aptamers that specifically bind to lactate dehydrogenase of Plasmodium falciparum through epitopic targeting

BACKGROUND: Early detection is crucial for the effective treatment of malaria, particularly in those cases infected with Plasmodium falciparum. There is a need for diagnostic devices with the capacity to distinguish P. falciparum from other strains of malaria. Here, aptamers generated against target...

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Detalles Bibliográficos
Autores principales: Frith, Kelly-Anne, Fogel, Ronen, Goldring, J. P. Dean, Krause, Robert G. E., Khati, Makobetsa, Hoppe, Heinrich, Cromhout, Mary E., Jiwaji, Meesbah, Limson, Janice L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934816/
https://www.ncbi.nlm.nih.gov/pubmed/29724225
http://dx.doi.org/10.1186/s12936-018-2336-z