Cargando…

The role of vimentin in the tumor marker Nup88-dependent multinucleated phenotype

BACKGROUND: Nucleoporin Nup88, a component of nuclear pore complexes, is known to be overexpressed in several types of tumor tissue. The overexpression of Nup88 has been reported to promote the early step of tumorigenesis by inducing multinuclei in both HeLa cells and a mouse model. However, the mol...

Descripción completa

Detalles Bibliográficos
Autores principales: Makise, Masaki, Nakamura, Hideaki, Kuniyasu, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934895/
https://www.ncbi.nlm.nih.gov/pubmed/29724197
http://dx.doi.org/10.1186/s12885-018-4454-y