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Application of a Pharmacokinetic Model of Metformin Clearance in a Population with Acute Myeloid Leukemia
OBJECTIVE: We aimed to estimate the metformin-associated lactic acidosis (MALA) risk by assessing retrospectively the renal clearance variability and applying a pharmacokinetic (PK) model of metformin clearance in a population diagnosed with acute myeloid leukemia (AML) and diabetes mellitus (DM). M...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934987/ https://www.ncbi.nlm.nih.gov/pubmed/29755998 http://dx.doi.org/10.4103/jrpp.JRPP_17_53 |