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Age-Related Increase of Insulin-Degrading Enzyme Is Inversely Correlated with Cognitive Function in APPswe/PS1dE9 Mice
BACKGROUND: Insulin-degrading enzyme (IDE) is an important regulator for Aβ clearance and diabetes. Although it is indispensable in removing plaques related to onset Alzheimer’s disease (AD) and in degrading insulin related to diabetes, there have been few studies on the dynamic level of IDE in diff...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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International Scientific Literature, Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935016/ https://www.ncbi.nlm.nih.gov/pubmed/29680859 http://dx.doi.org/10.12659/MSM.909596 |