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Complexities of post-transcriptional regulation and the modeling of ceRNA crosstalk

Control of gene and protein expression is required for cellular homeostasis and is disrupted in disease. Following transcription, mRNA turnover and translation is modulated, most notably by microRNAs (miRNAs). This modulation is controlled by transcriptional and post-transcriptional events that alte...

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Detalles Bibliográficos
Autores principales: Smillie, Claire L., Sirey, Tamara, Ponting, Chris P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935048/
https://www.ncbi.nlm.nih.gov/pubmed/29569941
http://dx.doi.org/10.1080/10409238.2018.1447542