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A biosensor for MAPK-dependent Lin28 signaling

Intracellular levels of the RNA-binding protein and pluripotency factor, Lin28a, are tightly controlled to govern cellular and organismal growth. Lin28a is extensively regulated at the posttranscriptional level, and can undergo mitogen-activated protein kinase (MAPK)–mediated elevation from low basa...

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Detalles Bibliográficos
Autores principales: Oldach, Laurel M., Gorshkov, Kirill, Mills, William T., Zhang, Jin, Meffert, Mollie K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935066/
https://www.ncbi.nlm.nih.gov/pubmed/29540527
http://dx.doi.org/10.1091/mbc.E17-08-0500