Intraflagellar transport is deeply integrated in hedgehog signaling

The vertebrate hedgehog pathway is organized in primary cilia, and hedgehog components relocate into or out of cilia during signaling. Defects in intraflagellar transport (IFT) typically disrupt ciliary assembly and attenuate hedgehog signaling. Determining whether IFT drives the movement of hedgeho...

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Detalles Bibliográficos
Autores principales: Eguether, Thibaut, Cordelieres, Fabrice P., Pazour, Gregory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935068/
https://www.ncbi.nlm.nih.gov/pubmed/29540531
http://dx.doi.org/10.1091/mbc.E17-10-0600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935068/
https://www.ncbi.nlm.nih.gov/pubmed/29540531
http://dx.doi.org/10.1091/mbc.E17-10-0600

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