The dynamic Atg13-free conformation of the Atg1 EAT domain is required for phagophore expansion

Yeast macroautophagy begins with the de novo formation of a double-membrane phagophore at the preautophagosomal structure/phagophore assembly site (PAS), followed by its expansion into the autophagosome responsible for cargo engulfment. The kinase Atg1 is recruited to the PAS by Atg13 through intera...

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Detalles Bibliográficos
Autores principales: Lin, Mary G., Schöneberg, Johannes, Davies, Christopher W., Ren, Xuefeng, Hurley, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935072/
https://www.ncbi.nlm.nih.gov/pubmed/29540529
http://dx.doi.org/10.1091/mbc.E17-04-0258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935072/
https://www.ncbi.nlm.nih.gov/pubmed/29540529
http://dx.doi.org/10.1091/mbc.E17-04-0258

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