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The dynamic Atg13-free conformation of the Atg1 EAT domain is required for phagophore expansion
Yeast macroautophagy begins with the de novo formation of a double-membrane phagophore at the preautophagosomal structure/phagophore assembly site (PAS), followed by its expansion into the autophagosome responsible for cargo engulfment. The kinase Atg1 is recruited to the PAS by Atg13 through intera...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935072/ https://www.ncbi.nlm.nih.gov/pubmed/29540529 http://dx.doi.org/10.1091/mbc.E17-04-0258 |