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Indole-3-Carbinol Promotes Goblet-Cell Differentiation Regulating Wnt and Notch Signaling Pathways AhR-Dependently

Using an in vitro model of intestinal organoids derived from intestinal crypts, we examined effects of indole-3-carbinol (I3C), a phytochemical that has anticancer and aryl hydrocarbon receptor (AhR)-activating abilities and thus is sold as a dietary supplement, on the development of intestinal orga...

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Detalles Bibliográficos
Autores principales: Park, Joo-Hung, Lee, Jeong-Min, Lee, Eun-Jin, Hwang, Won-Bhin, Kim, Da-Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935097/
https://www.ncbi.nlm.nih.gov/pubmed/29562732
http://dx.doi.org/10.14348/molcells.2018.2167