Cargando…

Indole-3-Carbinol Promotes Goblet-Cell Differentiation Regulating Wnt and Notch Signaling Pathways AhR-Dependently

Using an in vitro model of intestinal organoids derived from intestinal crypts, we examined effects of indole-3-carbinol (I3C), a phytochemical that has anticancer and aryl hydrocarbon receptor (AhR)-activating abilities and thus is sold as a dietary supplement, on the development of intestinal orga...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Joo-Hung, Lee, Jeong-Min, Lee, Eun-Jin, Hwang, Won-Bhin, Kim, Da-Jeong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935097/ https://www.ncbi.nlm.nih.gov/pubmed/29562732 http://dx.doi.org/10.14348/molcells.2018.2167

Ejemplares similares

Dietary Indole-3-Carbinol Activates AhR in the Gut, Alters Th17-Microbe Interactions, and Exacerbates Insulitis in NOD Mice
por: Kahalehili, Heather M., et al.
Publicado: (2021)

Aryl Hydrocarbon Receptor Ligands Indoxyl 3-sulfate and Indole-3-carbinol Inhibit FMS-like Tyrosine Kinase 3 Ligand-induced Bone Marrow-derived plasmacytoid Dendritic Cell Differentiation
por: Hwang, Won-Bhin, et al.
Publicado: (2018)

Indole-3-carbinol, a plant nutrient and AhR-Ligand precursor, supports oral tolerance against OVA and improves peanut allergy symptoms in mice
por: Hammerschmidt-Kamper, Christiane, et al.
Publicado: (2017)

Indol-3-Carbinol and Quercetin Ameliorate Chronic DSS-Induced Colitis in C57BL/6 Mice by AhR-Mediated Anti-Inflammatory Mechanisms
por: Riemschneider, Sina, et al.
Publicado: (2021)

The Landscape of AhR Regulators and Coregulators to Fine-Tune AhR Functions
por: Gargaro, Marco, et al.
Publicado: (2021)

AhR and Wnt/β-Catenin Signaling Pathways and Their Interplay
por: Grishanova, Alevtina Y., et al.
Publicado: (2023)

Tumor-Suppressive Functions of the Aryl Hydrocarbon Receptor (AhR) and AhR as a Therapeutic Target in Cancer
por: Elson, Daniel J., et al.
Publicado: (2023)

Serotonin Modulates AhR Activation by Interfering with CYP1A1-Mediated Clearance of AhR Ligands
por: Manzella, Christopher R., et al.
Publicado: (2020)

Coactivator Recruitment of AhR/ARNT1
por: Endler, Alexander, et al.
Publicado: (2014)

AhR signaling pathways and regulatory functions
por: Larigot, Lucie, et al.
Publicado: (2018)

Epigenetic Regulations of AhR in the Aspect of Immunomodulation
por: Wajda, Anna, et al.
Publicado: (2020)

AhR promotes phosphorylation of ARNT isoform 1 in human T cell malignancies as a switch for optimal AhR activity
por: Bourner, Luke A., et al.
Publicado: (2022)

AhR and IDO1 in pathogenesis of Covid-19 and the “Systemic AhR Activation Syndrome:” a translational review and therapeutic perspectives
por: Turski, Waldemar A., et al.
Publicado: (2020)

Ethyl Caffeate Can Inhibit Aryl Hydrocarbon Receptor (AhR) Signaling and AhR-Mediated Potentiation of Mast Cell Activation
por: Nguyen, Phuc-Tan, et al.
Publicado: (2023)

Gene expression profiling of the Notch-AhR-IL22 axis at homeostasis and in response to tissue injury
por: Weidenbusch, Marc, et al.
Publicado: (2017)

Role of AhR/ARNT system in skin homeostasis
por: Furue, Masutaka, et al.
Publicado: (2014)

Bidirectional talk between AhR and Oct4
por: Kang, Bo, et al.
Publicado: (2015)

Induction of AhR-Mediated Gene Transcription by Coffee
por: Ishikawa, Toshio, et al.
Publicado: (2014)

New Treatments in Renal Cancer: The AhR Ligands
por: Itkin, Boris, et al.
Publicado: (2020)

Herbal Plants: The Role of AhR in Mediating Immunomodulation
por: Bungsu, Izzah, et al.
Publicado: (2021)

Indole-3-propionic acid alleviates chondrocytes inflammation and osteoarthritis via the AhR/NF-κB axis
por: Zhuang, Huangming, et al.
Publicado: (2023)

The inhibition of lung cancer cell migration by AhR-regulated autophagy
por: Tsai, Chi-Hao, et al.
Publicado: (2017)

Role of the Arylhydrocarbon Receptor (AhR) in the Pathology of Asthma and COPD
por: Chiba, Takahito, et al.
Publicado: (2012)

Isopsoralen Enhanced Osteogenesis by Targeting AhR/ERα
por: Ge, Luna, et al.
Publicado: (2018)

AhR-deficiency as a cause of demyelinating disease and inflammation
por: Juricek, Ludmila, et al.
Publicado: (2017)

The Role of Aryl Hydrocarbon Receptor (AhR) in Brain Tumors
por: Perepechaeva, Maria L., et al.
Publicado: (2020)

AhR and Cancer: From Gene Profiling to Targeted Therapy
por: Paris, Anaïs, et al.
Publicado: (2021)

The Role of AhR in the Hallmarks of Brain Aging: Friend and Foe
por: Ojo, Emmanuel S., et al.
Publicado: (2021)

Molecular Docking of Natural Compounds for Potential Inhibition of AhR
por: Giordano, Deborah, et al.
Publicado: (2023)

AhR activation underlies the CYP1A autoinduction by A-998679 in rats
por: Liguori, Michael J., et al.
Publicado: (2012)

Effect of diet and intestinal AhR expression on fecal microbiome and metabolomic profiles
por: Yang, Fang, et al.
Publicado: (2020)

AhR transcriptional activity in serum of Inuits across Greenlandic districts
por: Long, Manhai, et al.
Publicado: (2007)

AhR-Mediated, Non-Genomic Modulation of IDO1 Function
por: Pallotta, Maria Teresa, et al.
Publicado: (2014)

AhR-Mediated Effects of Dioxin on Neuronal Acetylcholinesterase Expression in Vitro
por: Xie, Heidi Qunhui, et al.
Publicado: (2013)

The Coevolution of IDO1 and AhR in the Emergence of Regulatory T-Cells in Mammals
por: Grohmann, Ursula, et al.
Publicado: (2015)

The Role of Aryl-Hydrocarbon Receptor (AhR) in Osteoclast Differentiation and Function
por: Park, Robin, et al.
Publicado: (2020)

Pharmaceutically Active Microbial AhR Agonists as Innovative Biodrugs in Inflammation
por: Puccetti, Matteo, et al.
Publicado: (2022)

Developmental Origins of Delayed Adult Immune Response: The AhR Connection
por: Pascual, Florencia
Publicado: (2021)

Environmental exposure and the role of AhR in the tumor microenvironment of breast cancer
por: Sweeney, Colleen, et al.
Publicado: (2022)

The Role of the Kynurenine/AhR Pathway in Diseases Related to Metabolism and Cancer
por: Shadboorestan, Amir, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_i6ssrar86hsglm36j09d7np59v