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Proteomic Analysis of Early Diabetic Retinopathy Reveals Mediators of Neurodegenerative Brain Diseases

PURPOSE: Current evidence suggests that retinal neurodegeneration is an early event in the pathogenesis of diabetic retinopathy. Our main goal was to examine whether, in the diabetic human retina, common proteins and pathways are shared with brain neurodegenerative diseases. METHODS: A proteomic ana...

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Detalles Bibliográficos
Autores principales: Sundstrom, Jeffrey M., Hernández, Cristina, Weber, Sarah R., Zhao, Yuanjun, Dunklebarger, Mitchell, Tiberti, Natalia, Laremore, Tatiana, Simó-Servat, Olga, Garcia-Ramirez, Marta, Barber, Alistair J., Gardner, Thomas W., Simó, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935294/
https://www.ncbi.nlm.nih.gov/pubmed/29847632
http://dx.doi.org/10.1167/iovs.17-23678