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A Population Study of Common Ocular Abnormalities in C57BL/6N rd8 Mice

PURPOSE: The purpose of this study was to quantify the frequency and severity of ocular abnormalities affecting wild-type C57BL/6N mice, the most common strain used worldwide for the creation of single-gene knockouts. METHODS: A total of 2773 animals (5546 eyes) were examined at one colony at UC Dav...

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Detalles Bibliográficos
Autores principales: Moore, Bret A., Roux, Michel J., Sebbag, Lionel, Cooper, Ann, Edwards, Sydney G., Leonard, Brian C., Imai, Denise M., Griffey, Stephen, Bower, Lynette, Clary, Dave, Lloyd, K. C. Kent, Hérault, Yann, Thomasy, Sara M., Murphy, Christopher J., Moshiri, Ala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935295/
https://www.ncbi.nlm.nih.gov/pubmed/29847629
http://dx.doi.org/10.1167/iovs.17-23513