Cas13d is a compact RNA-targeting type VI CRISPR effector positively modulated by a WYL domain-containing accessory protein

Bacterial class 2 CRISPR-Cas systems utilize a single RNA-guided protein effector to mitigate viral infection. We aggregated genomic data from multiple sources and constructed an expanded database of predicted class 2 CRISPR-Cas systems. A search for novel RNA targeting systems identified subtype VI...

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Detalles Bibliográficos
Autores principales: Yan, Winston X., Chong, Shaorong, Zhang, Huaibin, Makarova, Kira S., Koonin, Eugene V., Cheng, David R., Scott, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935466/
https://www.ncbi.nlm.nih.gov/pubmed/29551514
http://dx.doi.org/10.1016/j.molcel.2018.02.028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935466/
https://www.ncbi.nlm.nih.gov/pubmed/29551514
http://dx.doi.org/10.1016/j.molcel.2018.02.028

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