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Palladium(0) catalyzed Suzuki cross-coupling reaction of 2,5-dibromo-3-methylthiophene: selectivity, characterization, DFT studies and their biological evaluations

Thiophene derivatives have shown versatile pharmacological activities. The Suzuki reaction proved a convenient method for C–C bond formations in organic molecules. In the present research work novel derivatives of 2,5-dibromo-3-methylthiophene (3a–k and 3l–p) has been synthesized, via Suzuki couplin...

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Detalles Bibliográficos
Autores principales: Rizwan, Komal, Zubair, Muhammad, Rasool, Nasir, Mahmood, Tariq, Ayub, Khurshid, Alitheen, Noorjahan Banu, Aziz, Muhammad Nazirul Mubin, Akhtar, Muhammad Nadeem, Nasim, Faiz-ul-Hassan, Bukhary, Snober Mona, Ahmad, Viqar Uddin, Rani, Mubeen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935605/
https://www.ncbi.nlm.nih.gov/pubmed/29728881
http://dx.doi.org/10.1186/s13065-018-0404-7