Cargando…
Palladium(0) catalyzed Suzuki cross-coupling reaction of 2,5-dibromo-3-methylthiophene: selectivity, characterization, DFT studies and their biological evaluations
Thiophene derivatives have shown versatile pharmacological activities. The Suzuki reaction proved a convenient method for C–C bond formations in organic molecules. In the present research work novel derivatives of 2,5-dibromo-3-methylthiophene (3a–k and 3l–p) has been synthesized, via Suzuki couplin...
Autores principales: | Rizwan, Komal, Zubair, Muhammad, Rasool, Nasir, Mahmood, Tariq, Ayub, Khurshid, Alitheen, Noorjahan Banu, Aziz, Muhammad Nazirul Mubin, Akhtar, Muhammad Nadeem, Nasim, Faiz-ul-Hassan, Bukhary, Snober Mona, Ahmad, Viqar Uddin, Rani, Mubeen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935605/ https://www.ncbi.nlm.nih.gov/pubmed/29728881 http://dx.doi.org/10.1186/s13065-018-0404-7 |
Ejemplares similares
-
Facile synthesis of N- (4-bromophenyl)-1- (3-bromothiophen-2-yl)methanimine derivatives via Suzuki cross-coupling reaction: their characterization and DFT studies
por: Rizwan, Komal, et al.
Publicado: (2018) -
Efficient Double Suzuki Cross-Coupling Reactions of 2,5-Dibromo-3-hexylthiophene: Anti-Tumor, Haemolytic, Anti-Thrombolytic and Biofilm Inhibition Studies
por: Ikram, Hafiz Mansoor, et al.
Publicado: (2016) -
Efficient Synthesis of Novel Pyridine-Based Derivatives via Suzuki Cross-Coupling Reaction of Commercially Available 5-Bromo-2-methylpyridin-3-amine: Quantum Mechanical Investigations and Biological Activities
por: Ahmad, Gulraiz, et al.
Publicado: (2017) -
Selective C-Arylation of 2,5-Dibromo-3-hexylthiophene via Suzuki Cross Coupling Reaction and Their Pharmacological Aspects
por: Ikram, Hafiz Mansoor, et al.
Publicado: (2015) -
Regioselective synthesis of 2-(bromomethyl)-5-aryl-thiophene derivatives via palladium (0) catalyzed suzuki cross-coupling reactions: as antithrombotic and haemolytically active molecules
por: Rizwan, Komal, et al.
Publicado: (2014)