Heterochromatin protein 1a functions for piRNA biogenesis predominantly from pericentric and telomeric regions in Drosophila

In metazoan germline, Piwi-interacting RNAs (piRNAs) provide defence against transposons. Piwi–piRNA complex mediates transcriptional silencing of transposons in nucleus. Heterochromatin protein 1a (HP1a) has been proposed to function downstream of Piwi-piRNA complex in Drosophila. Here we show that...

Descripción completa

Detalles Bibliográficos
Autores principales: Teo, Ryan Yee Wei, Anand, Amit, Sridhar, Vishweshwaren, Okamura, Katsutomo, Kai, Toshie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935673/
https://www.ncbi.nlm.nih.gov/pubmed/29728561
http://dx.doi.org/10.1038/s41467-018-03908-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935673/
https://www.ncbi.nlm.nih.gov/pubmed/29728561
http://dx.doi.org/10.1038/s41467-018-03908-3

Ejemplares similares