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Identification of brain antigens recognized by autoantibodies in experimental autoimmune encephalomyelitis-induced animals treated with etomoxir or interferon-β

Multiple sclerosis (MS) is a neurodegenerative autoimmune disease, where chronic inflammation plays an essential role in its pathology. A feature of MS is the production of autoantibodies stimulated by an altered-peptide-ligand response and epitope spreading, resulting in loss of tolerance for self-...

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Detalles Bibliográficos
Autores principales: Mørkholt, Anne Skøttrup, Kastaniegaard, Kenneth, Trabjerg, Michael Sloth, Gopalasingam, Gopana, Niganze, Wanda, Larsen, Agnete, Stensballe, Allan, Nielsen, Søren, Nieland, John Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935685/
https://www.ncbi.nlm.nih.gov/pubmed/29728570
http://dx.doi.org/10.1038/s41598-018-25391-y