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Roles of GalNAc-disialyl Lactotetraosyl Antigens in Renal Cancer Cells

GalNAc-disialyl Lc4 (GalNAc-DSLc4) was reported as a novel antigen that associated with malignant features of renal cell cancers (RCCs). To clarify roles of GalNAc-DSLc4 in malignant properties of RCCs, we identified B4GalNAc-T2 as a responsible gene for the synthesis of GalNAc-DSLc4, and prepared s...

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Detalles Bibliográficos
Autores principales: Tsuchida, Akiko, Senda, Motohiro, Ito, Akihiro, Saito, Seiichi, Kiso, Makoto, Ando, Takayuki, Harduin-Lepers, Anne, Matsuda, Akio, Furukawa, Keiko, Furukawa, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935701/
https://www.ncbi.nlm.nih.gov/pubmed/29728594
http://dx.doi.org/10.1038/s41598-018-25521-6