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Dysregulation of tristetraprolin and human antigen R promotes gastric cancer progressions partly by upregulation of the high-mobility group box 1

Aberrant expression of ARE-binding proteins (ARE-BPs) plays an important role in several diseases, including cancer. Both tristetraprolin (TTP) and human antigen R (HuR) are important ARE-BPs and always play opposite roles in regulating target mRNAs. Our previous work has demonstrated that TTP expre...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Chen, Yigang, Guo, Jian, Shan, Ting, Deng, Kaiyuan, Chen, Jialin, Cai, Liping, Zhou, Hong, Zhao, Qin, Jin, Shimao, Xia, Jiazeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935726/
https://www.ncbi.nlm.nih.gov/pubmed/29728635
http://dx.doi.org/10.1038/s41598-018-25443-3