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Can zinc protect cells from the cytotoxic effects of cobalt ions and nanoparticles derived from metal-on-metal joint arthroplasties?

OBJECTIVES: Recently, high failure rates of metal-on-metal (MOM) hip implants have raised concerns of cobalt toxicity. Adverse reactions occur to cobalt nanoparticles (CoNPs) and cobalt ions (Co(2+)) during wear of MOM hip implants, but the toxic mechanism is not clear. METHODS: To evaluate the prot...

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Detalles Bibliográficos
Autores principales: Liu, Y., Zhu, H., Hong, H., Wang, W., Liu, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935811/
https://www.ncbi.nlm.nih.gov/pubmed/29203637
http://dx.doi.org/10.1302/2046-3758.612.BJR-2016-0137.R2