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Effects of simvastatin in chronic obstructive pulmonary disease: Results of a pilot, randomized, placebo-controlled clinical trial

INTRODUCTION: Statins may have pleiotropic effects in COPD, but mechanisms remain unclear. OBJECTIVES: To assess the pleiotropic effect of statins in patients with stable COPD on (1): lung function (2); pulmonary and systemic inflammation (3); endothelial function (vascular stiffness) and circulatin...

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Detalles Bibliográficos
Autores principales: Balaguer, Catalina, Peralta, Alejandro, Ríos, Ángel, Iglesias, Amanda, Valera, Josep Lluís, Noguera, Aina, Soriano, Joan B., Agustí, Àlvar, Sala-Llinas, Ernest
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935853/
https://www.ncbi.nlm.nih.gov/pubmed/29736450
http://dx.doi.org/10.1016/j.conctc.2015.12.008