On clinical trials with a high placebo response rate

The basic problem that causes the frequent failure of a standard randomized parallel placebo-controlled clinical trial with a high placebo response rate is the underestimation of the treatment effect by the observed relative treatment difference. A two-period sequential parallel enrichment design ha...

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Detalles Bibliográficos
Autores principales: Chi, George Y.H., Li, Yihan, Liu, Yanning, Lewin, David, Lim, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935859/
https://www.ncbi.nlm.nih.gov/pubmed/29736445
http://dx.doi.org/10.1016/j.conctc.2015.10.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935859/
https://www.ncbi.nlm.nih.gov/pubmed/29736445
http://dx.doi.org/10.1016/j.conctc.2015.10.002

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