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Neuropilin-1 promotes the oncogenic Tenascin-C/integrin β3 pathway and modulates chemoresistance in breast cancer cells

BACKGROUND: Neuropilin-1 (NRP-1), a non-tyrosine kinase glycoprotein receptor, is associated with poor prognosis breast cancer, however transcriptomic changes triggered by NRP-1 overexpression and its association with chemoresistance in breast cancer have not yet been explored. METHODS: BT-474 NRP-1...

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Detalles Bibliográficos
Autores principales: Naik, Adviti, Al-Yahyaee, Aida, Abdullah, Nada, Sam, Juda-El, Al-Zeheimi, Noura, Yaish, Mahmoud W., Adham, Sirin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935908/
https://www.ncbi.nlm.nih.gov/pubmed/29728077
http://dx.doi.org/10.1186/s12885-018-4446-y