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Crosstalk between the Warburg effect, redox regulation and autophagy induction in tumourigenesis

Tumourigenic tissue uses modified metabolic signalling pathways in order to support hyperproliferation and survival. Cancer-associated aerobic glycolysis resulting in lactic acid production was described nearly 100 years ago. Furthermore, increased reactive oxygen species (ROS) and lactate quantitie...

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Detalles Bibliográficos
Autores principales: Gwangwa, Mokgadi Violet, Joubert, Anna Margaretha, Visagie, Michelle Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935986/
https://www.ncbi.nlm.nih.gov/pubmed/29760743
http://dx.doi.org/10.1186/s11658-018-0088-y