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Crosstalk between the Warburg effect, redox regulation and autophagy induction in tumourigenesis
Tumourigenic tissue uses modified metabolic signalling pathways in order to support hyperproliferation and survival. Cancer-associated aerobic glycolysis resulting in lactic acid production was described nearly 100 years ago. Furthermore, increased reactive oxygen species (ROS) and lactate quantitie...
Autores principales: | Gwangwa, Mokgadi Violet, Joubert, Anna Margaretha, Visagie, Michelle Helen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935986/ https://www.ncbi.nlm.nih.gov/pubmed/29760743 http://dx.doi.org/10.1186/s11658-018-0088-y |
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