Prevalence and Spectrum of BRCA1/2 Germline Mutations in Women with Breast Cancer in China Based on Next-Generation Sequencing

BACKGROUND: BRCA1 and BRCA2 (BRCA1/2) play important roles in the development of breast cancer, but information regarding BRCA1/2 mutations in Chinese females remains limited. The aim of this study was to investigate the prevalence and spectrum of BRCA1/2 mutations in China. MATERIAL/METHODS: In tot...

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Detalles Bibliográficos
Autores principales: Liang, Yi, Yang, Xuexi, Li, Hong, Zhu, Anna, Guo, Zhiwei, Li, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936051/
https://www.ncbi.nlm.nih.gov/pubmed/29681614
http://dx.doi.org/10.12659/MSM.905812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936051/
https://www.ncbi.nlm.nih.gov/pubmed/29681614
http://dx.doi.org/10.12659/MSM.905812

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