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Prevalence and Spectrum of BRCA1/2 Germline Mutations in Women with Breast Cancer in China Based on Next-Generation Sequencing

BACKGROUND: BRCA1 and BRCA2 (BRCA1/2) play important roles in the development of breast cancer, but information regarding BRCA1/2 mutations in Chinese females remains limited. The aim of this study was to investigate the prevalence and spectrum of BRCA1/2 mutations in China. MATERIAL/METHODS: In tot...

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Detalles Bibliográficos
Autores principales:	Liang, Yi, Yang, Xuexi, Li, Hong, Zhu, Anna, Guo, Zhiwei, Li, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2018
Materias:	Clinical Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936051/ https://www.ncbi.nlm.nih.gov/pubmed/29681614 http://dx.doi.org/10.12659/MSM.905812

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