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Iron homeostasis regulates facultative heterochromatin assembly in adaptive genome control

Iron metabolism is critical for sustaining life and maintaining human health. Here, we find that iron homeostasis is linked to facultative heterochromatin assembly and regulation of gene expression during adaptive genome control. We show that the fission yeast Clr4/Suv39h histone methyltransferase i...

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Detalles Bibliográficos
Autores principales: Gallagher, Pamela S., Larkin, Madeline, Thillainadesan, Gobi, Dhakshnamoorthy, Jothy, Balachandran, Vanivilasini, Xiao, Hua, Wellman, Christopher, Chatterjee, Raghunath, Wheeler, David, Grewal, Shiv I. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936480/
https://www.ncbi.nlm.nih.gov/pubmed/29686279
http://dx.doi.org/10.1038/s41594-018-0056-2