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The distribution of the modified Rankin scale scores change according to eligibility criteria in acute ischemic stroke trials: A consideration for sample size calculations when using ordinal regression analysis

BACKGROUND: Distribution shifts of the modified Rankin scale (mRs) is used as outcome measure in acute ischemic stroke (AIS) randomized controlled trials (RCT). Distribution across strata of mRs is relevant for sample size calculations and may be affected by eligibility criteria. AIM: We aimed to as...

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Detalles Bibliográficos
Autores principales: Olavarría, Verónica V., Brunser, Alejandro, Cabral, Norberto, Martins, Sheila, Muñoz-Venturelli, Paula, Cavada, Gabriel, Lavados, Pablo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936693/
https://www.ncbi.nlm.nih.gov/pubmed/29740628
http://dx.doi.org/10.1016/j.conctc.2017.01.008