Organoid cystogenesis reveals a critical role of microenvironment in human polycystic kidney disease

Polycystic kidney disease (PKD) is a life-threatening disorder, commonly caused by defects in polycystin-1 (PC1) or polycystin-2 (PC2), in which tubular epithelia form fluid-filled cysts (1, 2). A major barrier to understanding PKD is the absence of human cellular models that accurately and efficien...

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Detalles Bibliográficos
Autores principales: Cruz, Nelly M., Song, Xuewen, Czerniecki, Stefan M., Gulieva, Ramila E., Churchill, Angela J., Kim, Yong Kyun, Winston, Kosuke, Tran, Linh M., Diaz, Marco A., Fu, Hongxia, Finn, Laura S., Pei, York, Himmelfarb, Jonathan, Freedman, Benjamin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936694/
https://www.ncbi.nlm.nih.gov/pubmed/28967916
http://dx.doi.org/10.1038/nmat4994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936694/
https://www.ncbi.nlm.nih.gov/pubmed/28967916
http://dx.doi.org/10.1038/nmat4994

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