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Single cardiac ventricular myosins are autonomous motors

Myosin transduces ATP free energy into mechanical work in muscle. Cardiac muscle has dynamically wide-ranging power demands on the motor as the muscle changes modes in a heartbeat from relaxation, via auxotonic shortening, to isometric contraction. The cardiac power output modulation mechanism is ex...

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Detalles Bibliográficos
Autores principales: Wang, Yihua, Yuan, Chen-Ching, Kazmierczak, Katarzyna, Szczesna-Cordary, Danuta, Burghardt, Thomas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936712/
https://www.ncbi.nlm.nih.gov/pubmed/29669825
http://dx.doi.org/10.1098/rsob.170240