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Pathways for maintenance of telomeres and common fragile sites during DNA replication stress
Oncogene activation during tumour development leads to changes in the DNA replication programme that enhance DNA replication stress. Certain regions of the human genome, such as common fragile sites and telomeres, are particularly sensitive to DNA replication stress due to their inherently ‘difficul...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936717/ https://www.ncbi.nlm.nih.gov/pubmed/29695617 http://dx.doi.org/10.1098/rsob.180018 |