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Critical review: involvement of endoplasmic reticulum stress in the aetiology of Alzheimer's disease

The endoplasmic reticulum (ER) stress response is regarded as an important process in the aetiology of Alzheimer's disease (AD). The accumulation of pathogenic misfolded proteins and the disruption of intracellular calcium (Ca(2+)) signalling are considered to be fundamental mechanisms that und...

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Detalles Bibliográficos
Autores principales: Hashimoto, Shoko, Saido, Takaomi C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936719/
https://www.ncbi.nlm.nih.gov/pubmed/29695619
http://dx.doi.org/10.1098/rsob.180024