Hyperuricemia Induces Wnt5a/Ror2 Gene Expression, Epithelial–Mesenchymal Transition, and Kidney Tubular Injury in Mice

BACKGROUND: Hyperuricemia contributes to kidney injury, characterized by tubular injury with epithelial–mesenchymal transition (EMT). Wnt5a/Ror2 signaling drives EMT in many kidney pathologies. This study sought to evaluate the involvement of Wnt5a/Ror2 in hyperuricemia-induced EMT in kidney tubular...

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Detalles Bibliográficos
Autores principales: Setyaningsih, Wiwit Ananda Wahyu, Arfian, Nur, Suryadi, Efrayim, Romi, Muhammad Mansyur, Tranggono, Untung, Sari, Dwi Cahyani Ratna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Journal of Medical Sciences 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936848/
https://www.ncbi.nlm.nih.gov/pubmed/29749985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936848/
https://www.ncbi.nlm.nih.gov/pubmed/29749985

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