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Controlled fluorescence quenching by antibody-conjugated graphene oxide to measure tau protein

We report an ultrasensitive immunoassay for tau protein—a key marker of Alzheimer's disease. This sensing platform relies on graphene oxide (GO) surfaces conjugated with anti-human tau antibody to provide quantitative binding sites for the tau protein. The GO quenches standard fluorescein isoth...

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Detalles Bibliográficos
Autores principales: Huang, Ao, Zhang, Luning, Li, Weiwei, Ma, Zeyu, Shuo, Shi, Yao, Tianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936912/
https://www.ncbi.nlm.nih.gov/pubmed/29765647
http://dx.doi.org/10.1098/rsos.171808