Controversial Role of Kisspeptins/KiSS-1R Signaling System in Tumor Development

KiSS-1 was first described as a metastasis suppressor gene in malignant melanoma. KiSS-1 encodes a 145 amino-acid residue peptide that is further processed, producing the 54 amino acid metastin and shorter peptides collectively named kisspeptins (KPs). KPs bind and activate KiSS-1R (GPR54). Although...

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Detalles Bibliográficos
Autores principales: Fratangelo, Federica, Carriero, Maria Vincenza, Motti, Maria Letizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936968/
https://www.ncbi.nlm.nih.gov/pubmed/29760678
http://dx.doi.org/10.3389/fendo.2018.00192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936968/
https://www.ncbi.nlm.nih.gov/pubmed/29760678
http://dx.doi.org/10.3389/fendo.2018.00192

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