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Multiplexed Nanopore Sequencing of HLA-B Locus in Māori and Pacific Island Samples
The human leukocyte antigen (HLA) system encodes the human major histocompatibility complex (MHC). HLA-B is the most polymorphic gene in the MHC class I region and many HLA-B alleles have been associated with adverse drug reactions (ADRs) and disease susceptibility. The frequency of such HLA-B allel...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936980/ https://www.ncbi.nlm.nih.gov/pubmed/29760718 http://dx.doi.org/10.3389/fgene.2018.00152 |