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Dissemination of Orientia tsutsugamushi, a Causative Agent of Scrub Typhus, and Immunological Responses in the Humanized DRAGA Mouse

Scrub typhus is caused by Orientia tsutsugamushi, an obligated intracellular bacterium that affects over one million people per year. Several mouse models have been used to study its pathogenesis, disease immunology, and for testing vaccine candidates. However, due to the intrinsic differences betwe...

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Detalles Bibliográficos
Autores principales: Jiang, Le, Morris, Erin K., Aguilera-Olvera, Rodrigo, Zhang, Zhiwen, Chan, Teik-Chye, Shashikumar, Soumya, Chao, Chien-Chung, Casares, Sofia A., Ching, Wei-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936984/
https://www.ncbi.nlm.nih.gov/pubmed/29760694
http://dx.doi.org/10.3389/fimmu.2018.00816