Structure of Transmembrane Helix 8 and Possible Membrane Defects in CFTR

The cystic fibrosis transmembrane conductance regulator (CFTR) is an ion channel that regulates the flow of anions across epithelia. Mutations in CFTR cause cystic fibrosis. CFTR belongs to the ATP-binding cassette transporter superfamily, and gating is controlled by phosphorylation and ATP binding...

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Detalles Bibliográficos
Autores principales: Corradi, Valentina, Gu, Ruo-Xu, Vergani, Paola, Tieleman, D. Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2018
Materias:
Biophysical Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936993/
https://www.ncbi.nlm.nih.gov/pubmed/29694855
http://dx.doi.org/10.1016/j.bpj.2018.03.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936993/
https://www.ncbi.nlm.nih.gov/pubmed/29694855
http://dx.doi.org/10.1016/j.bpj.2018.03.003

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