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Emerging Concepts in Immune Thrombocytopenia

Immune thrombocytopenia (ITP) is an autoimmune disease defined by low platelet counts which presents with an increased bleeding risk. Several genetic risk factors (e.g., polymorphisms in immunity-related genes) predispose to ITP. Autoantibodies and cytotoxic CD8(+) T cells (Tc) mediate the anti-plat...

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Detalles Bibliográficos
Autores principales: Swinkels, Maurice, Rijkers, Maaike, Voorberg, Jan, Vidarsson, Gestur, Leebeek, Frank W. G., Jansen, A. J. Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937051/
https://www.ncbi.nlm.nih.gov/pubmed/29760702
http://dx.doi.org/10.3389/fimmu.2018.00880