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Emerging Concepts in Immune Thrombocytopenia
Immune thrombocytopenia (ITP) is an autoimmune disease defined by low platelet counts which presents with an increased bleeding risk. Several genetic risk factors (e.g., polymorphisms in immunity-related genes) predispose to ITP. Autoantibodies and cytotoxic CD8(+) T cells (Tc) mediate the anti-plat...
Autores principales: | Swinkels, Maurice, Rijkers, Maaike, Voorberg, Jan, Vidarsson, Gestur, Leebeek, Frank W. G., Jansen, A. J. Gerard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937051/ https://www.ncbi.nlm.nih.gov/pubmed/29760702 http://dx.doi.org/10.3389/fimmu.2018.00880 |
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