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Synergism of Antimicrobial Frog Peptides Couples to Membrane Intrinsic Curvature Strain
Mixtures of the frog peptides magainin 2 and PGLa are well-known for their pronounced synergistic killing of Gram-negative bacteria. We aimed to gain insight into the underlying biophysical mechanism by interrogating the permeabilizing efficacies of the peptides as a function of stored membrane curv...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937145/ https://www.ncbi.nlm.nih.gov/pubmed/29694871 http://dx.doi.org/10.1016/j.bpj.2018.03.006 |