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Use of functional respiratory imaging to characterize the effect of inhalation profile and particle size on lung deposition of inhaled corticosteroid/long-acting β2-agonists delivered via a pressurized metered-dose inhaler

BACKGROUND: Functional respiratory imaging (FRI) uses three-dimensional models of human lungs and computational fluid dynamics to simulate functional changes within airways and predict the deposition of inhaled drugs. This study used FRI to model the effects of different patient inhalation and drug...

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Detalles Bibliográficos
Autores principales: Van Holsbeke, Cedric, De Backer, Jan, Vos, Wim, Marshall, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937159/
https://www.ncbi.nlm.nih.gov/pubmed/29499614
http://dx.doi.org/10.1177/1753466618760948