Combining Polygenic Hazard Score With Volumetric MRI and Cognitive Measures Improves Prediction of Progression From Mild Cognitive Impairment to Alzheimer's Disease

Improved prediction of progression to Alzheimer's Disease (AD) among older individuals with mild cognitive impairment (MCI) is of high clinical and societal importance. We recently developed a polygenic hazard score (PHS) that predicted age of AD onset above and beyond APOE. Here, we used data...

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Dades bibliogràfiques
Autors principals: Kauppi, Karolina, Fan, Chun Chieh, McEvoy, Linda K., Holland, Dominic, Tan, Chin Hong, Chen, Chi-Hua, Andreassen, Ole A., Desikan, Rahul S., Dale, Anders M.
Format: Online Article Text
Idioma:English
Publicat: Frontiers Media S.A. 2018
Matèries:
Neuroscience
Accés en línia:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937163/
https://www.ncbi.nlm.nih.gov/pubmed/29760643
http://dx.doi.org/10.3389/fnins.2018.00260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937163/
https://www.ncbi.nlm.nih.gov/pubmed/29760643
http://dx.doi.org/10.3389/fnins.2018.00260

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