Mitochondrial pathway mediated by reactive oxygen species involvement in α-hederin-induced apoptosis in hepatocellular carcinoma cells

AIM: To investigate the antitumor activity of α-hederin in hepatocellular carcinoma (HCC) cells and its underlying mechanisms in vitro and in vivo. METHODS: SMMC-7721, HepG-2 and Huh-7 HCC cells were cultured in vitro and treated with α-hederin (0, 5 μmol/L, 10 μmol/L, 15 μmol/L, 20 μmol/L, 25 μmol/...

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Detalles Bibliográficos
Autores principales: Li, Jiao, Wu, Dan-Dan, Zhang, Ji-Xiang, Wang, Jing, Ma, Jing-Jing, Hu, Xue, Dong, Wei-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2018
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937207/
https://www.ncbi.nlm.nih.gov/pubmed/29740205
http://dx.doi.org/10.3748/wjg.v24.i17.1901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937207/
https://www.ncbi.nlm.nih.gov/pubmed/29740205
http://dx.doi.org/10.3748/wjg.v24.i17.1901

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