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Peptide Retention in Hydrophilic Strong Anion Exchange Chromatography Is Driven by Charged and Aromatic Residues

[Image: see text] Hydrophilic strong anion exchange chromatography (hSAX) is becoming a popular method for the prefractionation of proteomic samples. However, the use and further development of this approach is affected by the limited understanding of its retention mechanism and the absence of eluti...

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Detalles Bibliográficos
Autores principales: Giese, Sven H., Ishihama, Yasushi, Rappsilber, Juri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937359/
https://www.ncbi.nlm.nih.gov/pubmed/29528219
http://dx.doi.org/10.1021/acs.analchem.7b05157