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MiR-497-5p, miR-195-5p and miR-455-3p function as tumor suppressors by targeting hTERT in melanoma A375 cells

BACKGROUND: hTERT gene plays an important role in melanoma, although the specific mechanism involved is unclear. The aim of this study was to screen and identify the relative miRNAs with the regulation of hTERT in melanoma. MATERIALS AND METHODS: Quantitative real-time polymerase chain reaction (q-P...

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Detalles Bibliográficos
Autores principales: Chai, Li, Kang, Xiao-Jing, Sun, Zhen-Zhu, Zeng, Ming-Feng, Yu, Shi-Rong, Ding, Yuan, Liang, Jun-Qin, Li, Ting-Ting, Zhao, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937487/
https://www.ncbi.nlm.nih.gov/pubmed/29760567
http://dx.doi.org/10.2147/CMAR.S163335